Diffusion Approximations to Channel Noise
نویسنده
چکیده
A birth and death process is considered in which X,(t) is the number of open channels in a patch of membrane containing n channels. The voltage response of such a patch to conductance fluctuations is obtained including moments and spectral density. Furthermore, a diffusion approximation, an Ornstein-Uhlenbeck process, is obtained based on a weak convergence result to represent the patch conductance. Results are also obtained for a second diffusion approximation, that having the same first two infinitesimal moments as the birth and death process.
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